Proton pump inhibitor-induced risk of chronic kidney disease is associated with increase of indoxyl sulfate synthesis via inhibition of CYP2E1 protein degradation

Proton pump inhibitors affect the gut microbiome

Floris Imhann, Marc Jan Bonder, Arnau Vich Vila et al. · Gut · 2015 · 1.3K citations · Full text

Life Sciences, Microbiology, Pharmacology +15

Proton pump inhibitors alter the composition of the gut microbiota

Matthew Jackson, Julia K. Goodrich, Maria-Emanuela Maxan et al. · Gut · 2015 · 878 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

Jakk Wong, Yvette M. Piceno, Todd Z. DeSantis et al. · American Journal of Nephrology · 2014 · 632 citations · Full text

Life Sciences, Microbiology, Nutrition +17

Characterization of uremic toxin transport by organic anion transporters in the kidney

Tsuneo Deguchi, Hiroyuki Kusuhara, Akira Takadate et al. · Kidney International · 2003 · 238 citations · Full text

Life Sciences, Biochemistry, Nephrology +14

Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease

Derk C.F. Klatte, Alessandro Gasparini, Hong Xu et al. · Gastroenterology · 2017 · 163 citations · Full text

Medicine, Nephrology, Pharmacotherapy +9