Bioactivity analysis of calcium silicate‐based sealers and repair cements on the phenotype and cytokine secretion profile of <scp>CD14</scp>⁺ monocytes: An <i>ex vivo</i> study

Abstract

These data showed that the calcium silicate-based materials tested changed the morphology of CD14⁺ monocytes; however, only BioRoot-RCS and Biodentine significantly upregulated CD86. In addition, BioRoot-RCS was the sealer with the highest immunomodulatory properties for cytokine production which means that it can contribute with the in vivo healing process and regeneration of periapical lesions.