Prophylactic Use of Topical Antibiotic Irrigation in Uninfected Surgical Wounds

Abstract

In vitro experiments on the bacteriocidal effects of bacitracin and polymyxin B sulphate, alone and in combination, were done on a variety of microorganisms. The application of those studies to irrigation of surgical wounds with these topical antibodies in concentrations of twenty-five to fifty units per milliliter and twenty-five to fifty micrograms per milliliter respectively is suggested.