Cancer‐Associated Fibroblasts Hinder Lung Squamous Cell Carcinoma Oxidative Stress‐Induced Apoptosis via METTL3 Mediated m⁶A Methylation of COL10A1

Abstract

COL10A1 secreted by CAFs could facilitate LUSC cell proliferation and repress apoptosis-induced oxidative stress, and the mechanism was due to elevated expression mediated by METTL3 promoting its mRNA m⁶A modification, thereby accelerating tumor growth.