Endoscopic Treatment of Vesicoureteral Reflux in Patients With Myelodysplasia

Osamu Yokoyama, Yoshiyuki Ishiura, Chikashi Seto, Tadao Uchibayashi, Mitsuo Ohkawa

The Journal of Urology · 1996 · 14 citations · 19 references

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Abstract

No AccessJournal of UrologyClinical Urology: Original Article1 Jun 1996Endoscopic Treatment of Vesicoureteral Reflux in Patients With Myelodysplasia Osamu Yokoyama, Yoshiyuki Ishiura, Chikashi Seto, Tadao Uchibayashi, and Mitsuo Ohkawa Osamu YokoyamaOsamu Yokoyama More articles by this author , Yoshiyuki IshiuraYoshiyuki Ishiura More articles by this author , Chikashi SetoChikashi Seto More articles by this author , Tadao UchibayashiTadao Uchibayashi More articles by this author , and Mitsuo OhkawaMitsuo Ohkawa More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66038-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We assessed the usefulness of and indications for endoscopic treatment of vesicoureteral reflux in myelodysplasia patients. Materials and Methods: A total of 26 patients treated with intermittent catheterization was divided into 11 (16 ureters) with and 15 without vesicoureteral reflux. In 9 patients (13 ureters) endoscopic correction was performed with 3 percent atelo-collagen and without anesthesia at the outpatient clinic. In each ureter we obtained the sum of scores for 4 risk factors for upper urinary tract deterioration: bladder compliance less than 10 ml./cm. water, grade 2 to 3 bladder deformity, detrusor-sphincter dyssynergia and urethral closure pressure 50 cm. water or greater. Results: No reflux was demonstrated immediately after the initial collagen injection but cystography 3 to 6 months later showed recurrent reflux in 5 ureters (38 percent). Repeat injection cured the reflux, with results persisting for an average of 17 months. Mean risk factor score for patients without vesicoureteral reflux was significantly lower than that for patients with reflux. In patients treated with intermittent catheterization and anticholinergic agents the mean score for ureters with an increased or unchanged reflux grade was significantly greater than for those with a decreased grade. Conclusions: Endoscopic treatment of reflux appears to be safe and useful in patients with myelodysplasia. This treatment is preferable in those with high risk factor scores due to the possibility of increased reflux grade in such patients. References 1 : Fate of vesicoureteral reflux in children with neuropathic bladders managed by intermittent catheterization. J. Urol.1981; 125: 63. Link, Google Scholar 2 : The management of vesicoureteral reflux in the pediatric neurogenic bladder. J. Urol.1981; 125: 65. Link, Google Scholar 3 : The management of vesicoureteral reflux in children with myelodysplasia. J. Urol.1982; 128: 102. Link, Google Scholar 4 : Five-year experience with clean intermittent catheterization in children. Urology1982; 20: 128. Google Scholar 5 : The value of urodynamic testing in the management of neonates with myelodysplasia: a prospective study. J. Urol.1986; 135: 90. Google Scholar 6 : A prospective comparison of urinary tract infections in patients treated with either clean intermittent catheterization or urinary diversion. Pediatrics1982; 70: 665. Google Scholar 7 : The value of leak pressure and bladder compliance in the urodynamic evaluation of meningomyelocele patients. J. Urol.1990; 144: 1440. Link, Google Scholar 8 : Relevance of detrusor hyperreflexia, vesical compliance and urethral pressure to the occurrence of vesicoureteral reflux in myelodysplastic patients. J. Urol.1992; 147: 413. Link, Google Scholar 9 : Lower urinary tract function in myelomeningocele. Long-term follow-up data. Jap. J. Urol.1990; 81: 75. Google Scholar 10 : Die Behandlung des vesikorenalen Refluxes durch transurethrale Einspritzung von Teflonpaste. Urologe A1981; 20: 263. Google Scholar 11 : Pulmonary Teflon granulomas following periurethral Teflon injection for urinary incontinence. Arch. Path. Lab. Med.1983; 107: 611. Google Scholar 12 Medical versus surgical treatment of primary vesicoureteral reflux: report of the International Reflux Study Committee. Pediatrics1981; 67: 392. Google Scholar 13 : Subureteral collagen injection for the endoscopic treatment of vesicoureteral reflux in children. Followup study of 97 treated ureters and histological analysis of collagen implants. J. Urol.1992; 148: 718. Link, Google Scholar 14 : Endoscopic treatment of vesicoureteral reflux in children with neuropathic bladder. Ped. Surg. Int.1991; 6: 281. Google Scholar 15 : Endoscopic injection of glutaraldehyde cross-linked bovine dermal collagen for collection of vesicoureteral reflux. J. Urol.1991; 145: 115. Abstract, Google Scholar 16 : Endoscopic treatment of vesicoureteral reflux using cross-linked bovine dermal collagen. Ped. Surg. Int.1991; 6: 295. Google Scholar 17 : Correction of experimentally produced vesicoureteric reflux in the piglet by intravesical injection of Teflon. Brit. Med. J.1984; 289: 5. Google Scholar 18 : Local tissue reaction of the subureteral injection of glutaraldehyde cross-linked bovine collagen in humans. J. Urol.1990; 143: 1209. Abstract, Google Scholar 19 : A comparative study of the biologic and immunologic response to medical devices derived from dermal collagen. J. Biomed. Mater. Res.1986; 20: 109. Google Scholar 20 : An objective score to predict upper tract deterioration in myelodysplasia. J. Urol.1991; 145: 535. Link, Google Scholar 21 : Urodynamic patterns after acute spinal cord injury: association with bladder trabeculation in male patients. J. Urol.1983; 129: 777. Link, Google Scholar 22 : Clean intermittent self-catheterization: a 12-year followup. J. Urol.1990; 143: 906. Link, Google Scholar From the Department of Urology, School of Medicine, Kanazawa University, Kanazawa, Japan.© 1996 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byINOUE K, NAKAMOTO T, USUI A and USUI T (2018) ENDOSCOPIC SUBURETERAL GLUTARALDEHYDE CROSS-LINKED COLLAGEN INJECTION FOR THE TREATMENT OF SECONDARY VESICOURETERAL REFLUX: COMPARISON WITH PRIMARY VESICOURETERAL REFLUX IN ADULTSJournal of Urology, VOL. 164, NO. 2, (336-339), Online publication date: 1-Aug-2000.HAFERKAMP A, MÖHRING K, STAEHLER G, GERNER H and DÖRSAM J (2018) LONG-TERM EFFICACY OF SUBURETERAL COLLAGEN INJECTION FOR ENDOSCOPIC TREATMENT OF VESICOURETERAL REFLUX IN NEUROGENIC BLADDER CASESJournal of Urology, VOL. 163, NO. 1, (274-277), Online publication date: 1-Jan-2000. Volume 155Issue 6June 1996Page: 1882-1886 Advertisement Copyright & Permissions© 1996 by American Urological Association, Inc.MetricsAuthor Information Osamu Yokoyama More articles by this author Yoshiyuki Ishiura More articles by this author Chikashi Seto More articles by this author Tadao Uchibayashi More articles by this author Mitsuo Ohkawa More articles by this author Expand All Advertisement PDF downloadLoading ...

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