UNC Libraries · 2021 · 10 citations · 0 references
MedicineRadiation OncologyRadiologyDose-response ModelingRadiation DosimetryTreatment PlanningDose CalculationDose Uncertainty AnalysisOrgans At RiskPatient-specific DosimetryPlan OptimizationTreatment Planning Dose CalculationCumulative Organ At Risk DoseOrgan At Risk DosimetryOrgan Dose EstimationOrgan DosimetryTreatment Planning Dosimetry
Purpose: To build a statistical model to quantitatively correlate the anatomic features of structures and the corresponding dose-volume histogram (DVH) of head and neck (HN) Tomotherapy (Tomo) plans. To study if the model built upon one intensity modulated radiation therapy (IMRT) technique (such as conventional Linac) can be used to predict anticipated organs-at-risk (OAR) DVH of patients treated with a different IMRT technique (such as Tomo). To study if the model built upon the clinical experience of one institution can be used to aid IMRT planning for another institution.