THE TREATMENT OF GROSS HEMATURIA SECONDARY TO PROSTATIC BLEEDING WITH FINASTERIDE

Abstract

No AccessJournal of UrologyClinical Urology: Original Articles1 Apr 1998THE TREATMENT OF GROSS HEMATURIA SECONDARY TO PROSTATIC BLEEDING WITH FINASTERIDE PAUL R. SIEBER, F. MICHAEL ROMMEL, HENRY W. HUFFNAGLE, JOSEPH A. BRESLIN, VICTOR E. AGUSTA, and LEWIS E. HARPSTER PAUL R. SIEBERPAUL R. SIEBER , F. MICHAEL ROMMELF. MICHAEL ROMMEL , HENRY W. HUFFNAGLEHENRY W. HUFFNAGLE , JOSEPH A. BRESLINJOSEPH A. BRESLIN , VICTOR E. AGUSTAVICTOR E. AGUSTA , and LEWIS E. HARPSTERLEWIS E. HARPSTER View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)63567-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluate the use of finasteride to control gross hematuria secondary to prostatic bleeding. Materials and Methods: We reviewed retrospectively 42 patients treated with finasteride to treat gross hematuria. Results: There were 28 evaluable patients who had taken finasteride for at least 6 months to control gross hematuria and hematuria ceased in 25 (91%). In 1 patient clot retention developed requiring transurethral resection of the prostate and 2 patients had 1 or more minor episodes of bleeding that resolved spontaneously. Conclusions: Finasteride appears to be an effective agent for controlling gross hematuria secondary to prostatic bleeding. References 1 : The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. New Engl. J. Med.1992; 327: 1185. Google Scholar 2 : The clinical effects of a 5 alpha-reductase inhibitor, finasteride, on benign prostatic hyperplasia. J. Urol.1992; 147: 1298. Abstract, Google Scholar 3 : The effects of finasteride on hematuria associated with benign prostatic hyperplasia: a preliminary report. J. Urol.1995; 154: 1779. Link, Google Scholar 4 : Transurethral prostatectomy: immediate and postoperative complications. A cooperative study of 13 participating institutions evaluating 3,885 patients. J. Urol.1989; 141: 243. Abstract, Google Scholar 5 : Treatment of prostatic bleeding: suppression of angiogenesis by androgen deprivation. J. Urol.1993; 149: 1553. Link, Google Scholar 6 : Reduction in prostatic blood flow by finasteride. J. Urol.1997; 157: 190. part 2, abstract 738. Google Scholar Urological Associates of Lancaster, Ltd., Lancaster, Pennsylvania.© 1998 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByDONOHUE J, SHARMA H, ABRAHAM R, NATALWALA S, THOMAS D and FOSTER M (2018) Transurethral Prostate Resection and Bleeding: A Randomized, Placebo Controlled Trial of Role of Finasteride for Decreasing Operative Blood LossJournal of Urology, VOL. 168, NO. 5, (2024-2026), Online publication date: 1-Nov-2002.FOLEY S, SOLOMAN L, WEDDERBURN A, KASHIF K, SUMMERTON D, BASKETTER V and HOLMES S (2018) A PROSPECTIVE STUDY OF THE NATURAL HISTORY OF HEMATURIA ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA AND THE EFFECT OF FINASTERIDEJournal of Urology, VOL. 163, NO. 2, (496-498), Online publication date: 1-Feb-2000.BORBOROGLU P, KANE C, WARD J, ROBERTS J and SANDS J (2018) IMMEDIATE AND POSTOPERATIVE COMPLICATIONS OF TRANSURETHRAL PROSTATECTOMY IN THE 1990sJournal of Urology, VOL. 162, NO. 4, (1307-1310), Online publication date: 1-Oct-1999. Volume 159Issue 4April 1998Page: 1232-1233 Advertisement Copyright & Permissions© 1998 by American Urological Association, Inc.MetricsAuthor Information PAUL R. SIEBER More articles by this author F. MICHAEL ROMMEL More articles by this author HENRY W. HUFFNAGLE More articles by this author JOSEPH A. BRESLIN More articles by this author VICTOR E. AGUSTA More articles by this author LEWIS E. HARPSTER More articles by this author Expand All Advertisement PDF DownloadLoading ...