<i>In Vitro</i> Effects of Bisphenol A <b>β</b> -D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes

Abstract

To our knowledge, this study is the first to report that BPA-G induces adipocyte differentiation and is not simply an inactive metabolite. The fact that BPA-G induced adipogenesis and was inhibited by an ER antagonist yet showed no estrogenic activity suggests that it has no classical ER transcriptional activation function and acts through a pathway that remains to be determined.