Upper Tract Tumors in Patients with Primary Bladder Cancer Followed for 15 Years

Abstract

No AccessJournal of UrologyClinical Urology: Original Article1 Oct 1996Upper Tract Tumors in Patients with Primary Bladder Cancer Followed for 15 Years Harry W. Herr, Michael S. Cookson, and Scott M. Soloway Harry W. HerrHarry W. Herr , Michael S. CooksonMichael S. Cookson , and Scott M. SolowayScott M. Soloway View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)65570-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the long-term incidence of upper tract tumors in patients with primary superficial bladder cancer. Materials and Methods: A total of 86 patients with stages Ta, T1 and Tis bladder tumors, who were entered into a prospective trial of bacillus Calmette-Guerin between 1978 and 1981, was followed for 15 years or longer. Results: Of the 86 patients 18 (21 percent) had upper tract tumors after a median interval of 7.3 years (range 1 to 15). Tumors occurred within 5 years of followup in 6 cases, between 5 and 10 years in 7, and between 10 and 15 years in 5. The majority of cancers were invasive and 7 patients died of upper tract tumors. Conclusions: Patients with primary bladder tumors are at risk for upper urinary tract disease for up to 15 years, which suggests the need for lifelong regular upper tract monitoring in these cases. References 1 : Occurrence of uroepithelial tumors of the upper urinary tract after the initial diagnosis of bladder cancer. J. Urol.1988; 140: 745. Link, Google Scholar 2 : Urothelial tumors of upper tract following treatment of primary bladder transitional cell carcinoma. Urology1992; 40: 509. Google Scholar 3 : Upper urinary tract transitional cell cancer after radical cystectomy for bladder cancer. J. Urol.1984; 131: 50. Link, Google Scholar 4 : Development of upper tract carcinoma after cystectomy for bladder cancer. Urology1990; 36: 20. 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(2018) EDITORIAL COMMENTJournal of Urology, VOL. 160, NO. 1, (44-44), Online publication date: 1-Jul-1998.Montie J, Wojno K, Klein E, Pearsall C and Levin H (2018) TRANSITIONAL CELL CARCINOMA IN SITU OF THE SEMINAL VESICLES: 8 CASES WITH DISCUSSION OF PATHOGENESIS, AND CLINICAL AND BIOLOGICAL IMPLICATIONSJournal of Urology, VOL. 158, NO. 5, (1895-1898), Online publication date: 1-Nov-1997. Volume 156Issue 4October 1996Page: 1286-1287 Advertisement Copyright & Permissions© 1996 by American Urological Association, Inc.Metrics Author Information Harry W. Herr More articles by this author Michael S. Cookson More articles by this author Scott M. Soloway More articles by this author Expand All Advertisement PDF downloadLoading ...