Transfusion · 2022 · 16 citations · 12 references
MedicineCommunity HealthHealth PolicyCommunity-based Participatory ResearchHealth EquityTransfusion MedicineBlood Product ManagementBlood Transfusion ManagementBlood Transfusion SafetyRed Blood Cell TransfusionTransfusion TherapyTransfusion-transmitted InfectionsBlood Donor SafetyBlood Product UtilizationBlood Transfusion ReductionBlood Transfusion TherapyDonor Iron Deficiency PreventionHealth System ImplementationIron Deficiency RegulationTransfusion-associated Infection Prevention
BACKGROUND: The supply of blood in many low- and middle-income nations in Sub-Saharan Africa (SSA) does not meet the patient care needs. Lack and delay of blood transfusion cause harm to patients and slow the rate of progress in other parts of the health system. Recognizing the power of implementation science, the BLOODSAFE Program was initiated which supports three SSA research study teams and one data coordinating center (DCC) with the goal to improve access to safe blood transfusion in SSA. STUDY DESIGN AND METHODS: The study team in Ghana is focusing on studying and decreasing iron deficiency in blood donors and evaluating social engagement of blood donors through different approaches. The study team in Kenya is building a "vein to vein" workflow model to elucidate and devise strategies to overcome barriers to blood donation and improve infrastructural components of blood product production and use. The Malawi team is studying the infectious disease ramifications of blood donation as well as blood donor retention strategies aimed at blood donors who commence their donation career in secondary schools. RESULTS AND DISCUSSION: Together the project teams and the DCC work as a consortium to support each other through a shared study protocol that will study donor motivations, outcomes, and adverse events across all three countries. The BLOODSAFE Program has the potential to lead to generalizable improvement approaches for increasing access to safe blood in SSA as well as mentoring and building the research capacity and careers of many investigators.
12
Leontine Alkema, Doris Chou, Daniel Hogan et al. · The Lancet · 2015 · 2.3K citations · Full text
Daniel Dicker, Grant Nguyen, Degu Abate et al. · The Lancet · 2018 · 1.2K citations · Full text
Implementation research: new imperatives and opportunities in global health
Sally Theobald, Neal Brandes, Margaret Gyapong et al. · The Lancet · 2018 · 526 citations
The global need and availability of blood products: a modelling study
Nicholas L S Roberts, Spencer L James, Meghan Delaney et al. · The Lancet Haematology · 2019 · 238 citations