Paeoniflorin combined with norfloxacin ameliorates drug-resistant <i>Streptococcus suis</i> infection

Abstract

This study highlighted the inhibitory potential of paeoniflorin on the LuxS/AI-2 QS system of S. suis, and provided evidence that it can inhibit the FQ efflux pump and prevent biofilm formation to cooperate with norfloxacin in the treatment of resistant S. suis-related infections.