Cases Journal · 2009 · 13 citations · 6 references
MedicineHematologyHemostasisPediatric HematologyTransfusion MedicineCoagulation AbnormalitiesCoagulation DisordersCoagulation Factor DeficienciesHemostatic DisordersPlatelet FunctionPlatelet TransfusionBleedingBleeding ManifestationsCoagulationCoagulopathy-related BleedingFresh Frozen Plasma TherapyPediatric Bleeding DisordersRare Coagulation Factor DeficienciesTransfusion In Coagulopathy
Abnormal bleeding may result from deficiency of one of the clotting factors. A 13-year-old Indian girl, presented with a history of bleeding following minor injury, epistaxis, and hematuria, bleeding from gums, subcutaneous bleeding and gastro intestinal tract bleeding. She underwent a complete coagulation profile test, CT scan and ultrasound. Platelet Factor 3 dysfunction was diagnosed to be the cause of bleeding. Patient was transfused fresh frozen plasma and platelet as part of treatment. Condition of the patient after four months of diagnosis deteriorated and she started bleeding in tears and sweat. A thorough examination and proper workup are necessary to determine the exact cause and rule out serious conditions.
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Availability of Platelet Factor 3 and Activation of Factor XII in Thrombasthenia
P.A. Castaldi, M J Larrieu, J Caen · Nature · 1965 · 60 citations
Medicine, Hematology, Pathology +12