An iron(<scp>ii</scp>)-based metalloradical system for intramolecular amination of C(sp²)–H and C(sp³)–H bonds: synthetic applications and mechanistic studies

Abstract

)-H amination reactions involve a metalloradical activation mechanism, which is different from the previously reported electro-cyclization mechanism. Collectively, this study reports the discovery of a new class of metalloradical activation modes using a base metal catalyst that should find wide application in the context of medicinal chemistry, drug discovery and industrial applications.