ICTV Virus Taxonomy Profile: Hepeviridae 2022

Michael A. Purdy, Jan Felix Drexler, Xiang‐Jin Meng, Heléne Norder, Hiroaki Okamoto, Wim H. M. van der Poel, Gábor Reuter, William Marciel de Souza, Rainer G. Ulrich, Donald B. Smith

Journal of General Virology · 2022 · 312 citations · 3 references

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Abstract

The family Hepeviridae includes enterically transmitted small quasi-enveloped or non-enveloped positive-sense single-stranded RNA viruses infecting mammals and birds (subfamily Orthohepevirinae ) or fish ( Parahepevirinae ). Hepatitis E virus (genus Paslahepevirus ) is responsible for self-limiting acute hepatitis in humans; the infection may become chronic in immunocompromised individuals and extrahepatic manifestations have been described. Avian hepatitis E virus (genus Avihepevirus ) causes hepatitis–splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepeviridae , which is available at www.ictv.global/report/hepeviridae .

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