Expression of STING Is Increased in Monocyte-Derived Macrophages and Contributes to Liver Inflammation in Hepatic Ischemia-Reperfusion Injury

Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease

Jan Petrášek, Arvin Iracheta‐Vellve, Tímea Csák et al. · Proceedings of the National Academy of Sciences · 2013 · 453 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice

Xianjun Luo, Honggui Li, Linqiang Ma et al. · Gastroenterology · 2018 · 393 citations

Life Sciences, Immunology, Pathobiology +17

STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis

Yongsheng Yu, Yü Liu, Weishuai An et al. · Journal of Clinical Investigation · 2018 · 376 citations · Full text

Life Sciences, Immunology, Pathobiology +16

Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury

Yuan Liu, Tianfei Lu, Cheng Zhang et al. · Journal of Hepatology · 2019 · 277 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +14