Convenient Synthesis of <scp>Thioester‐Substituted</scp> Oxindoles by <scp>Palladium‐Catalyzed</scp> Thiocarbonylative Cyclization with Sulfonyl Chlorides as the Sulfur Source

Abstract

Comprehensive Summary A general and straightforward strategy for the synthesis of thioester‐substituted oxindoles via a palladium‐catalyzed thiocarbonylative cyclization process has been developed. With sulfonyl chlorides as promising sulfur source, a wide range of thioester‐substituted oxindoles were obtained in moderate to high yields. Both aryl and alkyl sulfonyl chlorides were well tolerated, and Mo(CO) 6 played a dual role as both a CO source and a reductant in this approach.