Design, Synthesis, DFT, Molecular Docking, and Biological Evalution of Pyrazole Derivatives as Potent Acetyl Cholinestrease Inhibitors

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.6K citations

Biochemistry, Acetylcholinesterase Activity, Medicine +4

Is It Reliable to Take the Molecular Docking Top Scoring Position as the Best Solution without Considering Available Structural Data?

David Ramírez, Julio Caballero · Molecules · 2018 · 531 citations · Full text

Engineering, Structural Bioinformatics, Best Docking Solution +19

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

Osama I. El‐Sabbagh, Mohamed M. Baraka, Samy M. Ibrahim et al. · European Journal of Medicinal Chemistry · 2009 · 367 citations

Medicinal Chemistry, Medicine, New Pyrazole +7

Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility

Jonah Cheung, E. Gary, Kazuro Shiomi et al. · ACS Medicinal Chemistry Letters · 2013 · 272 citations · Full text

Drug Target, Neurochemical Biomarkers, Chemical Biology +16

A new therapeutic approach in Alzheimer disease: Some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics

Nesrin Gökhan-Kelekçi, Samiye Yabanoğlu, Esra Küpeli̇ et al. · Bioorganic & Medicinal Chemistry · 2007 · 227 citations · Full text

Pharmaceutical Science, Alzheimer's Disease, Novel Pyrazole Derivatives +11