Brønsted acid-catalyzed cascade cyclization: an efficient strategy for divergent synthesis of cyclohepta[<i>b</i>]indole derivatives

Abstract

An efficient acid-catalyzed three-component cascade strategy by employing 3,3′-bis(indolyl)methanes (BIMs) as masked 1,4-nucleophiles was established for synthesizing cyclohepta[ b ]indoles under mild and eco-friendly conditions.