Concepedia

DFV890: a new oral NLRP3 inhibitor—tested in an early phase 2a randomised clinical trial in patients with COVID-19 pneumonia and impaired respiratory function

Ildikó Madurka, Alexander Vishnevsky, Joan B. Soriano, Stephanus J. Gans, Danilo Joel Salazar Ore, Adrián Rendón, Charlotte Suppli Ulrik, Sushma Bhatnagar, Srikanth V. Krishnamurthy, Kirsten Mc Harry,

Infection · 2022 · 83 citations · 19 references

DOIFull text

Open access

Concepts

References

19

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou, Xing‐Lou Yang, Xian-Guang Wang et al. · Nature · 2020 · 23.3K citations · Full text

, , +14

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

JAMA · 2020 · 21.2K citations · Full text

, , +11

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

, , +16

APACHE II-A Severity of Disease Classification System

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

, , +12

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

Xiaobo Yang, Yu Yuan, Jiqian Xu et al. · The Lancet Respiratory Medicine · 2020 · 10.7K citations · Full text

, , +14