Concepedia

Curcumin Improves Keratinocyte Proliferation, Inflammation, and Oxidative Stress through Mediating the SPAG5/FOXM1 Axis in an In Vitro Model of Actinic Dermatitis by Ultraviolet

Quan Chen, Yi Tang, Huiyan Deng, Bihua Liang, Huaping Li, Zhenjie Li, Huilan Zhu, Lezi Chen

Disease Markers · 2022 · 11 citations · 17 references

DOIFull text

Open access

Abstract

Curcumin modulated proliferation, inflammation, oxidative stress, and apoptosis of keratinocytes by restraining the SPAG5/FOXM1 axis.

References

17

Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

Jae-We Cho, Kun Park, Gi Ryang Kweon et al. · Experimental & Molecular Medicine · 2005 · 148 citations · Full text

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SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation

Hongliang Liu, Junwen Hu, Ran Wei et al. · Journal of Experimental & Clinical Cancer Research · 2018 · 112 citations · Full text

SPAG5‐AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway

Jun Xu, Yujie Deng, Yi Wang et al. · Cell Proliferation · 2020 · 103 citations · Full text

SPAG5: An Emerging Oncogene

Ji He, Andrew R. Green, Yan Li et al. · Trends in cancer · 2020 · 76 citations · Full text

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Protective Effect of Curcumin Against Acute Ultraviolet B Irradiation‐induced Photo‐damage

Huaping Li, Aili Gao, Na Jiang et al. · Photochemistry and Photobiology · 2016 · 63 citations