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MASSIVE OSTEOLYSIS (ACUTE SPONTANEOUS ABSORPTION OF BONE, PHANTOM BONE, DISAPPEARING BONE)
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1955
Year
Progressive OsteolysisOsteopathyVascular MalformationPathologyOsteogenesisSurgeryOsteoporosisOrthopaedic SurgeryBone DiseaseActive HyperaemiaDisappearing BoneNew SyndromeHealth SciencesBone HealthBone DensityMassive OsteolysisBone MetabolismPhantom BoneBone ImagingPhysiologyMedicineConnective Tissue Disease
A new syndrome of massive osteolysis has been identified in 24 cases, showing consistent clinical, radiographic, and histologic findings, and is always associated with angiomatosis of blood and sometimes lymphatic vessels, though mechanisms remain unexplored. The study seeks to determine whether massive osteolysis results from hyperemia, mechanical forces, pH changes, or other causes, but this cannot yet be established. Other information includes items 1, 2, and 3.
1. There now exists the basis for a new syndrome which is supported by a remarkable similarity of clinical and roentgenographic findings in twenty-four cases, and by an equally convincing similarity of the histological picture in eight of these, which we have personally studied. 2. However it is accomplished, the progressive osteolysis is always associated with an angiomatosis of blood and sometimes of lymphatic vessels, which seemingly are responsible for it. 3. A discussion of the possible mechanism involved is outside the province of this paper. Whether massive osteolysis occurs as the direct result of active hyperaemia, of mechanical causes, of slight changes in pH, or from other causes cannot be established at the present time.