Diffusion mixing with a volatile tertiary amine as a very efficient technique for 1,3-dipolar cycloaddition reactions proceeding <i>via</i> dehydrohalogenation of stable precursors of reactive dipoles

Abstract

Spontaneous diffusion of tertiary amine vapors into a dipolarophile precursor solution is the simplest technique for nitrilylide and nitrilimine generation in 1,3-cycloaddition reactions.