Concepedia

1,2,3-Triazole Tethered Hybrid Capsaicinoids as Antiproliferative Agents Active against Lung Cancer Cells (A549)

Arif Khan, Fatima Naaz, Rafia Basit, Deepak Kumar Das, Piyush Bisht, Majeed Shaikh, Bilal Ahmad Lone, Yuba Raj Pokharel, Qazi Naveed Ahmed, Shazia Parveen,

ACS Omega · 2022 · 15 citations · 36 references

DOIFull text

Open access

Concepts

Abstract

has emerged as a lead molecule and may serve as a template for further discovery of capsaicinoid scaffolds.

References

36

Anticancer Properties of Capsaicin Against Human Cancer.

Ruth Clark, Seong‐Ho Lee · PubMed · 2016 · 298 citations

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Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region"

Christopher Walpole, Roger Wrigglesworth, Stuart Bevan et al. · Journal of Medicinal Chemistry · 1993 · 163 citations · Full text

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Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways

Jing Yang, Tai-Qin Li, Guangquan Xu et al. · Neoplasma · 2013 · 119 citations · Full text

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1,2,3-Triazoles of 8-Hydroxyquinoline and HBT: Synthesis and Studies (DNA Binding, Antimicrobial, Molecular Docking, ADME, and DFT)

Nidhi Nehra, Ram Kumar Tittal, Vikas D. Ghule · ACS Omega · 2021 · 108 citations · Full text

, , +16

1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

Fatima Naaz, M Pallavi, Syed Shafi et al. · Bioorganic Chemistry · 2018 · 102 citations

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