Concepedia

The induction of PANoptosis in KRAS-mutant pancreatic ductal adenocarcinoma cells by a multispecific platinum complex

Xin Yuan, Shuren Zhang, Xuanmeng Zhong, Hao Yuan, Dongfan Song, Xiaoyu Wang, Hanyang Yu, Zijian Guo

Science China Chemistry · 2022 · 14 citations · 22 references

DOI

Concepts

References

22

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

, , +14

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.2K citations · Full text

, , +9

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

, , +13

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

Xiaofeng Zheng, Julienne L. Carstens, Jiha Kim et al. · Nature · 2015 · 2K citations · Full text

, , +16

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

Duanwu Zhang, Jing Shao, Juan Lin et al. · Science · 2009 · 1.9K citations

, , +16