Concepedia

The clinical features and prognoses of anti-MDA5 and anti-aminoacyl-tRNA synthetase antibody double-positive dermatomyositis patients

Xixia Chen, Lu Zhang, Qiwen Jin, Xin Lü, Jieping Lei, Qinglin Peng, Guochun Wang, Yongpeng Ge

Frontiers in Immunology · 2022 · 11 citations · 27 references

DOIFull text

Open access

Abstract

Presentation with anti-MDA5+/ARS+ DM was rare. The clinical and radiological characteristics of anti-MDA5+/ARS+ DM combined the features of anti-MDA5+ and anti-ARS+ individuals. Individuals with anti-MDA5+/ARS+ antibodies may respond well to glucocorticoid therapy; glucocorticoids combined with one or more immunosuppressants may be considered a basic treatment approach.

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