Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV)

Abstract

Intravitreally delivered retinal multicell-derived exosomes have good retinal penetration, and ASL modification of exosomes actively targets CNV with no immediate reactive gliosis. ASL exosomes have a great potential to serve as an intraocular drug delivery vehicle, allowing an active targeting strategy.