Gut microbiota on admission as predictive biomarker for acute necrotizing pancreatitis

Abstract

Our study suggests that NP patients have distinct intestinal microbiota on admission compared to non-NP patients. Dysbiosis of intestinal microbiota might influence NP progression through ketone body or benzoate metabolism. <i>Enterococcus faecium</i> and <i>Finegoldia magna</i> are potential predictors for NP and infected NP. Our findings explore biomarkers which may inform clinical decision-making in AP and shed light on further studies on NP pathophysiology and management.