Detection of a Novel African Swine Fever Virus with Three Large-Fragment Deletions in Genome, China

Yankuo Sun, Zhiying Xu, Han Gao, Sijia Xu, Jing Liu, Jiabao Xing, Qiyuan Kuang, Yang Chen, Heng Wang, Guihong Zhang

Microbiology Spectrum · 2022 · 17 citations · 13 references

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Abstract

African swine fever virus (ASFV) has been circulating in China for 5 years, and low virulent strains with changes in the genome have been reported. Nevertheless, there is still a lack of knowledge about the epidemic strains at the whole-genome level. This study reported a novel strain and further analyzed its genomic and biological characteristics. In addition, our study also suggests that whole-genome sequencing plays a key role in the epidemiology investigation of ASFV variations.

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