Design and synthesis of spirooxindole–pyrrolidines embedded with indole and pyridine heterocycles by multicomponent reaction: anticancer and <i>in silico</i> studies

Abstract

We report the synthesis of spirooxindole–pyrrolidines tethered with indole and pyridine heterocycles using 1,3-dipolar cycloaddition, and their anticancer activities and molecular docking studies.