Mass spectrometry-based multi-attribute method for mutation analysis in the early development of therapeutic proteins

Mutation nomenclature extensions and suggestions to describe complex mutations: A discussion

Johan T. den Dunnen, Stylianos E. Antonarakis · Human Mutation · 2000 · 1.8K citations · Full text

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The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

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Life Sciences, Immunology, Molecular Biology +17

Ofatumumab As Single-Agent CD20 Immunotherapy in Fludarabine-Refractory Chronic Lymphocytic Leukemia

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Pharmacy, Oncology, Pharmacotherapy +17

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics

Richard S. Rogers, Nancy S. Nightlinger, Brittney Livingston et al. · mAbs · 2015 · 222 citations · Full text

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +16

Ocrelizumab, a humanized anti‐CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo‐controlled, dose‐ranging study

Mark C. Genovese, Jeffrey Kaine, Mitchell B. Lowenstein et al. · Arthritis & Rheumatism · 2008 · 205 citations

Medicine, Pharmacology, Pharmacotherapy +16