Dupilumab Is Effective in Patients With Moderate-to-Severe Uncontrolled GINA-Defined Type 2 Asthma Irrespective of an Allergic Asthma Phenotype

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

Mario Castro, Jonathan Corren, Ian Pavord et al. · New England Journal of Medicine · 2018 · 1.9K citations · Full text

Pharmacy, Immunology, Pharmacology +13

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

Prescott G. Woodruff, Barmak Modrek, David F. Choy et al. · American Journal of Respiratory and Critical Care Medicine · 2009 · 1.8K citations · Full text

Life Sciences, Immunology, Internal Medicine +16

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma

Klaus F. Rabe, Parameswaran Nair, Guy Brusselle et al. · New England Journal of Medicine · 2018 · 1.2K citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

Sally E. Wenzel, Mario Castro, Jonathan Corren et al. · The Lancet · 2016 · 880 citations

Medicine, Internal Medicine, Pharmacology +13

Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis

Ikuo Hirano, Evan S. Dellon, Jennifer D. Hamilton et al. · Gastroenterology · 2019 · 451 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +16