JACS Au · 2022 · 51 citations · 33 references
EngineeringBioengineeringBiomedical EngineeringBiocatalysisBioreactor DesignNanobiotechnologyBiocatalyst EngineeringCatalytic MechanismsNanomedicineNanostructured BiomaterialsPhotocatalysisPhotodynamic TherapyAntimicrobial Photodynamic TherapyDiabetic ComplicationsDiabetic Wound HealingDiabetic Wound PathophysiologyDiabetic Wound RepairHypoxiaPhotobioreactor ConstructionPhotodynamic Antimicrobial Therapy
into toxic reactive oxygen species by the photobiocatalytic cascade. As a result, it readily reverses the microenvironment of the diabetes wound and exhibits an extraordinary capacity for wound healing through synergistic photodynamic therapy. This work describes the first example of constructing an all-in-one HOF bioreactor for antimicrobial diabetes wound treatment and showcases the promise of combined biocatalysis and photocatalysis achieved by using an HOF scaffold in biomedicine applications.
33