Concepedia

Catalytic asymmetric cyclopropanation of sulfoxonium ylides catalyzed by a chiral-at-metal rhodium complex

Siliang Ming, Jian Yang, Shi Wu, Gang Yao, Hongwei Xiong, Yu Du, Jun Gong

Organic Chemistry Frontiers · 2022 · 15 citations · 71 references

DOI

Concepts

Abstract

An efficient asymmetric cyclopropanation of sulfoxonium ylides with α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium complex has been developed.

References

71

The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules

Tanaji T. Talele · Journal of Medicinal Chemistry · 2016 · 989 citations · Full text

, , +7

Catalytic, Asymmetric Sulfur Ylide-Mediated Epoxidation of Carbonyl Compounds:  Scope, Selectivity, and Applications in Synthesis

Varinder K. Aggarwal, C. L. Winn · Accounts of Chemical Research · 2004 · 513 citations

, , +13

Ylide-Initiated Michael Addition−Cyclization Reactions beyond Cyclopropanes

Xiu‐Li Sun, Yong Tang · Accounts of Chemical Research · 2008 · 409 citations

, , +15

Steering Asymmetric Lewis Acid Catalysis Exclusively with Octahedral Metal-Centered Chirality

Lilu Zhang, Eric Meggers · Accounts of Chemical Research · 2017 · 339 citations

, , +16

Asymmetric Photocatalysis with Bis-cyclometalated Rhodium Complexes

Xiaoqiang Huang, Eric Meggers · Accounts of Chemical Research · 2019 · 264 citations

, , +13