Adrenocortical Carcinoma

Tobias Else, Alex C. Kim, Aaron Sabolch, Victoria M. Raymond, Asha Kandathil, Elaine M. Caoili, Shruti Jolly, Barbra S. Miller, Thomas J. Giordano, Gary D. Hammer

Endocrine Reviews · 2013 · 887 citations · 312 references

Concepts

Abstract

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable prognosis. Here we summarize the knowledge about diagnosis, epidemiology, pathophysiology, and therapy of ACC. Over recent years, multidisciplinary clinics have formed and the first international treatment trials have been conducted. This review focuses on evidence gained from recent basic science and clinical research and provides perspectives from the experience of a large multidisciplinary clinic dedicated to the care of patients with ACC.

References

312