Soft Matter · 2022 · 23 citations · 46 references
Natural SciencesBioengineeringBiomedical EngineeringBiomaterialsDrug DeliveryPharmaceutical RheologyAntimicrobial BiomaterialsAntimicrobial PeptidesGelsHydrogel BiomaterialsHydrogelsPeptide DeliveryAntibacterial HydrogelsAntibacterial MaterialsAntibacterial PeptidesAntibacterial PropertiesControlled Drug ReleaseControlled ReleaseRheological CharacterizationSelf-assembling Peptide Hydrogels
. The antibacterial effect of the hydrogels was predominantly due to the osmotic stress and membrane disruption, which was verified by reactive oxygen species (ROS) generation and outer membrane permeabilization assays. Our findings point to the scope of using the synthesized peptide hydrogels as agents for topical applications.
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