Mitochondria-targeted alginate/triphenylphosphonium-grafted-chitosan for treatment of hepatocellular carcinoma

Kholoud K. Arafa, Mohamed A. Hamzawy, Shaker A. Mousa, Ibrahim M. El‐Sherbiny

RSC Advances · 2022 · 29 citations · 22 references

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Abstract

studies demonstrated an enhanced antitumor bioactivity for the mitotropic NPs along with a reduced biological toxicity profile. In conclusion, this study proposes a promising nanocarrier system for the efficient targeting of DOX to the mitochondria of hepatic tumors.

References

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