Taste GPCRs and their ligands

Highly accurate protein structure prediction with AlphaFold

John Jumper, Alexander Pritzel, Tim Green et al. · Nature · 2021 · 42K citations · Full text

Accurate prediction of protein structures and interactions using a three-track neural network

Minkyung Baek, Frank DiMaio, Ivan Anishchenko et al. · Science · 2021 · 5.4K citations · Full text

Substitution of three amino acids switches receptor specificity of Gqα to that of Giα

Bruce R. Conklin, Zvi Farfel, Kevin D. Lustig et al. · Nature · 1993 · 731 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +8

Gustducin is a taste-cell-specific G protein closely related to the transducins

Susan K. McLaughlin, Peter J. McKinnon, Robert F. Margolskee · Nature · 1992 · 673 citations

Biochemistry, Taste-cell-specific G Protein, Biomolecular Engineering +1

Bitter and sweet taste receptors regulate human upper respiratory innate immunity

Robert J. Lee, Jennifer M. Kofonow, Philip L. Rosen et al. · Journal of Clinical Investigation · 2014 · 403 citations · Full text

Asthma, Microbial Pathogens, Lung Inflammation +16