Automated Treatment Planning in Radiation Therapy using Generative\n Adversarial Networks

Rafid Mahmood, Aaron Babier, Andrea McNiven, Adam Diamant, Timothy C. Y. Chan

arXiv (Cornell University) · 2018 · 70 citations · 0 references

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Abstract

Knowledge-based planning (KBP) is an automated approach to radiation therapy\ntreatment planning that involves predicting desirable treatment plans before\nthey are then corrected to deliverable ones. We propose a generative\nadversarial network (GAN) approach for predicting desirable 3D dose\ndistributions that eschews the previous paradigms of site-specific feature\nengineering and predicting low-dimensional representations of the plan.\nExperiments on a dataset of oropharyngeal cancer patients show that our\napproach significantly outperforms previous methods on several clinical\nsatisfaction criteria and similarity metrics.\n