Scientific Reports · 2022 · 23 citations · 23 references
ComputingComputer ScienceNeurologyDementiaMachine LearningNatural Language ProcessingClinical Natural Language ProcessingDementia DiagnosisNatural Language UnderstandingNeurocognitive DisordersRepresentation LearningText Feature EngineeringFree-text Data ExtractionNeural Text RepresentationVector Data Representation
Recent NLP studies have identified dementia using structured tasks, but free conversation offers a simpler, less learning‑biased alternative for clinical use. This study aimed to build a machine‑learning model that distinguishes dementia from non‑dementia subjects by extracting features from unstructured free conversation. Researchers recruited outpatient dementia patients and healthy volunteers, transcribed their conversations, performed morphological analysis to convert sentences into real‑valued vectors, and used these vectors as features for the model. Across 432 datasets, the model achieved 90 % accuracy, 88.1 % sensitivity, and 91.6 % specificity in discriminating dementia from non‑dementia subjects.
Abstract In recent years, studies on the use of natural language processing (NLP) approaches to identify dementia have been reported. Most of these studies used picture description tasks or other similar tasks to encourage spontaneous speech, but the use of free conversation without requiring a task might be easier to perform in a clinical setting. Moreover, free conversation is unlikely to induce a learning effect. Therefore, the purpose of this study was to develop a machine learning model to discriminate subjects with and without dementia by extracting features from unstructured free conversation data using NLP. We recruited patients who visited a specialized outpatient clinic for dementia and healthy volunteers. Participants’ conversation was transcribed and the text data was decomposed from natural sentences into morphemes by performing a morphological analysis using NLP, and then converted into real-valued vectors that were used as features for machine learning. A total of 432 datasets were used, and the resulting machine learning model classified the data for dementia and non-dementia subjects with an accuracy of 0.900, sensitivity of 0.881, and a specificity of 0.916. Using sentence vector information, it was possible to develop a machine-learning algorithm capable of discriminating dementia from non-dementia subjects with a high accuracy based on free conversation.
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Tiia Ngandu, Jenni Lehtisalo, Alina Solomon et al. · The Lancet · 2015 · 3.6K citations
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