Concepedia

PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis

Xiaofeng Li, Shu-qin Yin, Hao Li, Yingli Yang, Xin Chen, Biao Song, Sha Wu, Yuanyuan Wu, Hua Wang, Jun Li

Acta Pharmacologica Sinica · 2022 · 44 citations · 17 references

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References

17

Distinct fibroblast subsets drive inflammation and damage in arthritis

Adam P. Croft, Joana Campos, Kathrin Jansen et al. · Nature · 2019 · 954 citations · Full text

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15-deoxy-Δ12,14-PGJ2 induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

Yutaka Kawahito, Motoharu Kondo, Yasunori Tsubouchi et al. · Journal of Clinical Investigation · 2000 · 376 citations · Full text

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PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice

Xiaobo Zhu, Fang Chen, Ke Lu et al. · Annals of the Rheumatic Diseases · 2019 · 117 citations

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TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis

Christopher Loh, Sungho Park, Angela Lee et al. · Annals of the Rheumatic Diseases · 2019 · 114 citations · Full text

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PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension

Jan K. Hennigs, Aiqin Cao, Caiyun G. Li et al. · Circulation Research · 2020 · 86 citations · Full text

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