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Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease

Sarah Macedo Vaz, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimarães, Fernanda Motta R. da Silva, Newton G. Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Gabriela Beserra Pinheiro, Letícia Germino Veras,

Bioorganic & Medicinal Chemistry · 2022 · 11 citations · 21 references

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21

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

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Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes

Richard A. Friesner, Robert B. Murphy, Matthew P. Repasky et al. · Journal of Medicinal Chemistry · 2006 · 6.9K citations

, , +16

Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands

Jonah Cheung, M. Rudolph, F. Burshteyn et al. · Journal of Medicinal Chemistry · 2012 · 1.3K citations

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Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer’s Disease

Kris Simone Tranches Dias, Cláudio Viegas · Current Neuropharmacology · 2014 · 171 citations · Full text

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Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25–35) oligomer-induced toxicity

Andrea Tarozzi, Fabiana Morroni, Adriana Merlicco et al. · Neuroscience Letters · 2010 · 98 citations

, , +16