Distribution and clinical significance of circulating CD8+CD28− regulatory T cells in the peripheral blood of patients with pulmonary tuberculosis

Abstract

This study was the first to show that the proportion of CD8⁺CD28^- Treg cells in the peripheral blood of patients with PTB was significantly increased, and the increase in CD8⁺CD28^- Treg cells was related to the progression of PTB, which may affect the proportion of immune cell subsets by inhibiting the immune response, resulting in the progression of PTB.