Publication | Closed Access
DMSO as a dual carbon synthon in one-pot tandem synthesis of <i>N</i>-alkylated quinazolinones from anthranilamides and acetophenones
13
Citations
48
References
2022
Year
Dual Carbon SynthonDmso-assisted ApproachEngineeringOne-pot Tandem SynthesisDual RoleAryl Methyl KetonesOrganic ChemistryCatalysisChemistryHeterocycle ChemistrySynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
DMSO-assisted approach for the synthesis of N -alkylated quinazolinones from readily available 2-aminobenzamide and aryl methyl ketones has been developed. DMSO played a dual role, acting as a solvent as well as a dual carbon synthon, making this process an environmentally benign approach.
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