Dual action of ketamine confines addiction liability

Antidepressant effects of ketamine in depressed patients

Robert Berman, Angela Cappiello, Amit Anand et al. · Biological Psychiatry · 2000 · 3.8K citations

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Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Bita Moghaddam, Barbara W. Adams, Anita Verma et al. · Journal of Neuroscience · 1997 · 1.8K citations · Full text

Medicine, Neuroscience, Pharmacology +14

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

Panos Zanos, Ruin Moaddel, Patrick J. Morris et al. · Nature · 2016 · 1.6K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Evidence for Addiction-like Behavior in the Rat

Véronique Deroche‐Gamonet, David Belin, Pier Vincenzo Piazza · Science · 2004 · 1.1K citations

Nursing, Neuroscience, Psychology +15

NMDA Receptor-Dependent Long-Term Potentiation and Long-Term Depression (LTP/LTD)

Christian Lüscher, Robert C. Malenka · Cold Spring Harbor Perspectives in Biology · 2012 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17