Rational design of flexible microneedles coupled with CaO<sub>2</sub>@PDA-loaded nanofiber films for skin wound healing on diabetic rats

Zhiyong Zeng, Guohua Jiang, Yanfang Sun, Uladzislau E. Aharodnikau, Khaydar E. Yunusov, Xiaofei Gao, Tianqi Liu, Sergey O. Solomevich

Biomaterials Science · 2022 · 55 citations · 49 references

Concepts

Abstract

@PDA nanoparticles demonstrated a high level of CD31 and low level of TNF-α, leading to accelerated diabetic skin-wound closure. These distinctive features demonstrate that our microneedle system can be a facile candidate for efficient wound healing in patients with diabetes and may be applied in various biomedical fields.

References

49