Frontiers in Bioengineering and Biotechnology · 2022 · 30 citations · 40 references
Natural SciencesBiomedical EngineeringMaterials EngineeringBiomaterialsMechanical Behavior Of MaterialsTissue EngineeringBioceramicsPorous MaterialsMinimal Surface StructuresPore Size EffectsSelective Laser MeltingTriply Periodic Minimal Surfaces
The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size continuous gradient distribution) and were successfully prepared using a novel Ni 46.5 Ti 44.5 Nb 9 alloy and selective laser melting (SLM) technology. After that, the effects of the pore strategies on the microstructure, mechanical properties, and permeability of porous scaffolds were systematically investigated. The results showed that the Ni 46.5 Ti 44.5 Nb 9 scaffolds have a low elastic modulus (0.80–1.05 GPa) and a high ductility (15.3–19.1%) compared with previous works. The pore size has little effect on their mechanical properties, but increasing the pore size significantly improves the permeability due to the decrease in specific surfaces. The continuous gradient distribution of the pore size changes the material distribution of the scaffold, and the smaller porosity structure has a better load-bearing capacity and contributes primarily to the high compression strength. The local high porosity structure bears more fluid flow, which can improve the permeability of the overall scaffold. This work can provide theoretical guidance for the design of porous scaffolds.
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Sajad Arabnejad, R. Burnett Johnston, Jenny Ann Pura et al. · Acta Biomaterialia · 2015 · 576 citations · Full text
Natural Sciences, Materials Engineering, Materials Science +17