Prevalence of hypervirulent and carbapenem-resistant <i>Klebsiella pneumoniae</i> under divergent evolutionary patterns

Abstract

mutation reduced capsular synthesis and increased carbapenem resistance of the CR-hvKp strain. In summary, this study revealed that hv-CRKP strains were more suitable for survival in hospital settings than CR-hvKp strains and the widespread conjugative KPC-producing plasmids contributed to the emergence and prevalence of hv-CRKP strains.