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Antidepressant effects of ketamine in depressed patients

Robert Berman, Angela Cappiello, Amit Anand et al. · Biological Psychiatry · 2000 · 3.8K citations

Medicine, Pharmacology, Psychiatry +14

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Bita Moghaddam, Barbara W. Adams, Anita Verma et al. · Journal of Neuroscience · 1997 · 1.8K citations · Full text

Medicine, Neuroscience, Pharmacology +14

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

Panos Zanos, Ruin Moaddel, Patrick J. Morris et al. · Nature · 2016 · 1.6K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression

Ella Daly, Madhukar H. Trivedi, Adam Janik et al. · JAMA Psychiatry · 2019 · 759 citations · Full text

Pharmacy, Pharmacotherapy, Psychiatry +17

History and evolution of the monoamine hypothesis of depression.

Robert M. A. Hirschfeld · PubMed · 2000 · 692 citations

Medicine, Neuroscience, Psychiatry +17