Manually-operated, slider cassette for multiplexed molecular detection at the point of care

CRISPR–Cas12-based detection of SARS-CoV-2

James P. Broughton, Xianding Deng, Guixia Yu et al. · Nature Biotechnology · 2020 · 2.8K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +8

SHERLOCK: nucleic acid detection with CRISPR nucleases

Max J. Kellner, Jeremy Koob, Jonathan S. Gootenberg et al. · Nature Protocols · 2019 · 1.6K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

An integrated rotary microfluidic system with DNA extraction, loop-mediated isothermal amplification, and lateral flow strip based detection for point-of-care pathogen diagnostics

Byung Hyun Park, Seung Jun Oh, Jae Hwan Jung et al. · Biosensors and Bioelectronics · 2016 · 238 citations

Engineering, Bioengineering, Biotechnology +17

A fully disposable and integrated paper-based device for nucleic acid extraction, amplification and detection

Ruihua Tang, Hui Yang, Yan Gong et al. · Lab on a Chip · 2017 · 192 citations

Engineering, Biomedical Engineering, Biotechnology +16

Chitosan as a Polymer for pH-Induced DNA Capture in a Totally Aqueous System

Weidong Cao, Christopher J. Easley, Jerome P. Ferrance et al. · Analytical Chemistry · 2006 · 166 citations

Engineering, Bioengineering, Biotechnology +16