New-onset pemphigus vegetans and pemphigus foliaceus after SARS-CoV-2 vaccination: A report of 2 cases

Abstract

New-onset and relapsed pemphigus vulgaris (PV), the most common variants of pemphigus, have been reported in association with vaccination against several infectious agents, including SARS-CoV-2.1 However, given the rarity of these events, much remains unknown about the clinical course of pemphigus after vaccination with the Pfizer mRNA BNT162b2 and Moderna mRNA-1273 vaccines, particularly among patients with diagnoses of less common subtypes. Here, we report 2 cases of new-onset pemphigus vegetans (PVeg) and pemphigus foliaceus (PF) after administration of the SARS-CoV-2 vaccine.